BlackBerry is primarily known for its ability to send and receive e-mail wherever it can access an appropriate wireless network of certain cellular phone carriers. It has a built-in keyboard, optimized for "thumbing", the use of only the thumbs to type. System navigation is primarily accomplished by the trackwheel (or "thumbwheel"), a scrolling wheel with a "click" function, located on the right side of the device. Some models (currently, those manufactured for use with Nextel, TELUS, and other iDEN networks) also incorporate a two-way radio. Some BlackBerry devices don't depend on mobile phone service coverage and are Wi-Fi compatible like similar handheld devices that are on the marketplace.

The devices are very popular with some businesses, where they are primarily used to provide e-mail access to roaming employees.